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专利名称：NEW 1,4-DIHYDROPYRIDINE ESTERS AND
PREPARATION METHODS THEREOF ANDDRUGS CONTAINING SAID ESTERS
发明人：SUNKEL LETELIER, CARLOS,FAU DE CASA-JUANA MUNOZ, MIGUEL,STATKOV, PETER,R.,STRAUMANN, DANIELLE
申请号：EP83903371.9申请日：19831118公开号：EP0126094B1公开日：19900620
摘要：1,4-dihydropyridine esters, and their salts, of formula (i) in which r is a hydrogenatom, a saturated or unsaturated hydrocarbon is alkylmorpholinique, or group.r2 and r3denote a hydrogen atom or an alkyl group, n is 0, 1, 2 or 3, and x denotes an aryl group) isa cycloalc\ényle, styryl, cycloalkyl, or a naphthyl.quinolyle, isoquinolyle, pyridyl,pyrimidyl, diphenyl substituted furyl, pyrryle or thioph\ényle eventually.r1 denotesa hydrocarbon is straight and branched chain saturated, unsaturated or cyclic.which maybe interrupted by one or two oxygen or sulfur atoms and substituted by one or twohydroxy groups.r1 can also refer to the group; (ii) means: (a) the n-substituted amides,nicotinic acid, salicylic acid and 4-hydroxybenzoic or monoalkyl\ées
piperazines.monoacyl\ées or n-substituted sulfonyl\ées of formula (iii) and (b) agroup of formula - ooc - r6 and r6 (in which r6 is an unsaturated cyclic hydrocarbon issaturated, branched or not, or,aromatic heterocyclic, or which may be substituted; (c) thestay 2 and n - (4 - t\étrahydrofuryle benzoylpip\éridinyle).we prepare 1,4-
dihydropyridine esters, and their salts useful as pharmacologically active ingredients.inparticular, the drugs for the treatment of cardiovascular disorders.
申请人：CERMOL S.A.,CERMOL S.A.
代理机构：Vuille, Roman
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