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专利名称:ORAL DELIVERY COMPOSITION FORMING A
MICROEMULSION
发明人:FARAH, NABIL,DENIS, JOEL申请号:EP949228.0申请日:19940929公开号:EP0670715A1公开日:19950913
摘要:Drug or cosmetic composition form microemulsion, contain at least one activeconstituent; The glyceride and aliphatic ester of the mixture of lipophilic phasecomposition; Surfactant (SA); Cosurfactant (CoSA); The hydrophilic sexual stage. Thecomposition is characterized in that lipophilic mutually by mixture C 8-C10polyglycolyzed glycerides, has hydrophilic lipophilic balance (HLB) less than 16,
oleophylic is mutually the total weight of the composition from 30 to 75%. It is a featureof the present invention that it includes saturated polyglycolysed glyceride and above-mentioned polyglycereol C8-C10 oleate esters that surfactant (sulphur), which is
selected from, which has HLB less than 16. Of the invention to be further characterized inthat, it includes the lauric ester of propylene glycol, Unigly GO 102S class and diethyleneglycol (DEG) ethyl that cosurfactant (CoS), which is selected from,; Because S/CoS ratiosare 0.5 to 6; And because the final microemulsion of aqueous favoring obtains afterintake by the medium of the digestion of physiological liquid.
申请人:GATTEFOSSE HOLDING
地址:36 chemin de Genas F-69800 Saint Priest FR
国籍:FR
代理机构:Vuillermoz, Bruno, et al
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