专利内容由知识产权出版社提供
专利名称：Indole derivatives, process for their
preparation and pharmaceuticalcompositions containing them
发明人：Malen, Charles,Lacoste, Jean-Michel,Laubie,
Michel
申请号：EP403356.2申请日：191205公开号：EP0373061A1公开日：19900613
摘要：the invention relates to compounds of the general formula: in which: a, b, c, d,identical or different, each representing a hydrogen atom or a halogen atom, an alkoxygroup, a lower alkyl group, lower, or may be substituted by one or more halogen atoms,and x represents a hydrogen atom.a linear or branched lower alkyl group or a groupwhich is a s02e (lower alkyl group, or aryl optionally substituted linear or branched loweralkyl group in a linear or branched, represents a hydrogen atom or a group or loweralkyl.r3 represents a hydrogen atom or a lower alkyl group, linear or branched,
substituted or aryl group or lower alkyl groups, by one or more linear ouramifi\és, nand m are each the same or different 0 or 1, and r, and r2 is the same or different eachrepresent hydrogen atom or a lower alkyl group, linear or branched.alternatively, r1 andr2 together with the nitrogen atom form a heterocyclic ring system to which they aremono or bicyclic nitrogen saturated or not, each cycle consisting of five plus six vertices,and possibly one or two other heteroatoms selected from nitrogen, oxygen or sulfur,and vent one or more blocking us substituted by alkyl or alkoxy groups, linear or
branched, loweror an aryl group optionally substituted by a - or lower alkoxy lower alkyl,several groups, trifluoromethyl, or one or more halogen atoms, and r1 is a group. inwhich r4, rs, rs, identical or different, represent each a hydrogen atom or a lower alkylgroup, linear or branched, or - ed form with a bridge (ch2) p, where p is between 2 and 4,or r1 represents a dibenzo [a, d] cycloheptyl 5 and r2 represents a hydrogen atom.whereappropriate, their isomers and their salts with a pharmaceutically acceptable acid additionproducts.
申请人：ADIR ET COMPAGNIE
地址：1 rue Carle Hébert F-92415 Courbevoie Cédex FR
国籍：FR
更多信息请下载全文后查看
